Assistant Professor of Chemistry Colleen Krause, students, and colleagues have developed a simple, inexpensive disposable test strip that detects Human Epidermal Growth Factor Receptor 2 (HER-2), a clinically relevant breast cancer biomarker. A manuscript of their findings has been accepted by the top biosensor journal, Biosensors Bioelectronics.
Krause says the disposable test strip costs just 25 cents to manufacture, and could easily be scaled for commercial use. “Current clinical methods to detect breast cancer often relies on imaging technology and invasive biopsies that can often miss cancerous cells at the early onset of disease,” she says. “Earlier detection for breast cancer will improve on patient survival rates and reduce cost of treatment globally.”
In the future, it is possible this biomarker test strip could be purchased at a local pharmacy, and would be a quick and easy method to detect HER 2, which is one of the few potential protein biomarkers for breast cancer approved by the FDA. It would make it possible for patients to be screened for cancer without having to undergo an invasive procedure.